心血管疾病,24小时运动行为和全因死亡率:基于前性队列的组成调解分析
Yutai Cai1, Ziqiang Lin1, Mengqu Liang1
1Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China.
心血管疾病 (CVD) 死亡率显著受到24小时运动行为的影响,特别是中度至剧烈的体力活动 (MVPA) 和久坐行为 (SB). 为心血管疾病患者量身定制体育活动可以延长寿命.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 心血管疾病 (CVD) 构成了全球严重的健康负担.
- 了解生活方式行为和心血管疾病结果之间的相互作用对于有效的预防和管理至关重要.
- 24小时运动行为,包括睡眠,久坐行为 (SB) 和体力活动,越来越被认为是健康的关键决定因素.
研究的目的:
- 调查24小时运动行为在心血管疾病 (CVD) 和死亡率之间的关联中的调解作用.
- 在心血管疾病患者的不同死亡风险层中描述24小时时间使用模式.
主要方法:
- 利用90858名英国生物库参与者的数据,其中30.7%患有心血管疾病,通过加速度计进行评估.
- 采用考克斯组合调解模型来分析24小时运动行为的调解效应.
- 使用风险分层和同时代替代模型确定24小时的时间使用模式.
主要成果:
- 通过24小时运动行为观察到心血管疾病对死亡率的显著间接影响,中度至强度体力活动 (MVPA) 占16.9%,SB占1.1%.
- 患有低死亡风险的心血管疾病患者表现出明显的24小时模式:433分钟的睡眠,606分钟的SB,310分钟的光强度体力活动和91分钟的MVPA.
- 随着死亡风险的增加,身体活动水平逐渐下降;高风险的心血管疾病患者通过采用低风险的时间使用模式,可以增加1.8年的寿命.
结论:
- 24小时运动行为,特别是MVPA和SB,显著调解心血管疾病和死亡率之间的关系.
- 针对心血管疾病患者的个性化体育活动干预措施,与与较低风险相关的24小时时间使用模式保持一致,是延长寿命的有希望的策略.
更多相关视频
11:21Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
Published on: July 27, 2018
07:51Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
相关概念视频
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Coronary Artery Disease I: Introduction
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Coronary Artery Disease III: Clinical Manifestations
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
