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Yajing Liu, Weixi Feng, Abulimiti Aikedan

    bioRxiv : the preprint server for biology
    |March 11, 2026
    PubMed
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    循环GMP-AMP合成酶 (cGAS) 驱动动神经元损失和RNA拼接缺陷在肌缩侧面硬化症 (ALS). 在临床前模型中抑制cGAS逆转了病理并保留了运动功能,提供了一个新的治疗点.

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