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Updated: Mar 12, 2026

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向基化酶10A破坏瘤微环境中的MAPK信号通路,释放抗瘤免疫力

Md Y Gazi, Yan Ye, Ogacheko D Okoko

    bioRxiv : the preprint server for biology
    |March 11, 2026
    PubMed
    概括

    一种新的PDE10A抑制剂ADT-030通过增强抗瘤免疫力和破坏癌细胞信号传递,有效抑制瘤生长. 它的有效性依赖于T细胞和树突细胞,这表明一种有前途的免疫治疗方法.

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