在Aphidinae虫中, (E) -β-farnesene信号传递的进化根深蒂固的气味受体
Tianyu Huang1,2, Lulu Yang1, Ying Tian1
1State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
iScience
|March 11, 2026
概括
虫使用 (E) - 贝塔-法尔内森 (EBF) 作为一个关键的警报激素,被特定的气味受体 (ORs) 检测到. 这项研究揭示了在Aphidinae虫中检测EBF的多受体系统,促进了嗅觉进化理解.
科学领域:
- 昆虫化学生态学 昆虫化学生态学
- 进化生物学是进化的生物学.
- 神经伦理学 神经伦理学
背景情况:
- 警报费洛蒙对于社会昆虫的生存至关重要,它们调解掠食者逃生.
- 警报费洛蒙的进化与嗅觉识别系统的发展有关.
- 了解这种共同进化的分子基础至关重要.
研究的目的:
- 为了分析各种虫物种的警报费洛蒙组成.
- 识别和描述参与检测警报信号的嗅觉受体 (ORs).
- 研究这些受体的进化动态及其与费洛蒙使用的关系.
主要方法:
- 在36种虫物种中对警报费洛蒙成分的比较分析.
- 13种虫物种的基因组注释,以确定保存和特定的OR.
- 选择的ORs (OR5,OR40,OR43) 对于EBF选择性的功能性表征.
- 在 *Acyrthosiphon pisum* 中进行基因淘汰实验,以评估排斥性中的受体功能.
- 遗传学分析可以追踪已识别的OR基因的进化史.
主要成果:
- 化合物 (E) - 贝塔法尔内森 (EBF) 被确定为Aphidinae亚家族中的主要警报信号.
- 在强烈净化选择下,确定了8个保存的,针对Aphidinae的OR分类.
- 三种受体 (OR5,OR40,OR43) 在阿菲迪纳群中显示出EBF选择性.
- 淘汰这些ORs显著减少了EBF诱导的排斥力,表明非冗余的角色.
- 遗传学分析显示,在不使用EBF的物种中,基因丢失,支持适应性进化.
结论:
- 青叶虫 (Aphidinae aphids) 拥有多受体系统,可以检测警报费洛蒙EBF.
- 已识别的ORs (OR5,OR40,OR43) 在EBF感知中扮演着特定的,非冗余的角色.
- 这种嗅觉系统的演变与EBF作为警报信号的使用密切相关,受体基因损失与缺失相关.
- 这项研究提供了关于嗅觉系统在应对适应性压力的分子机制和进化轨迹的见解.
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