当图像复活时:一个案例系列
Frédéric Bertrand1, Mélanie Strauss1,2, Gil Leurquin-Sterk3
1Department of Neurology, Hôpital Universitaire de Bruxelles, Anderlecht, Brussels, Belgium.
BMJ neurology open
|March 11, 2026
概括
患有痴呆症的患者可能会经历一种新的妄想误认综合征 (DMS) 变体,相信图片中的人还活着. 这种"动画图片综合征"表明认知能力下降,需要进一步研究.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 认知科学 认知科学
背景情况:
- 妄想误认综合征 (DMS) 与精神和神经疾病,特别是痴呆症有关.
- 在痴呆症患者中报告了一种新的DMS变体:相信静态图像中的个体是活着的.
研究的目的:
- 在痴呆症患者中描述以前未报告的幻觉误认综合征 (DMS) 变体.
- 描述这种综合征的临床表现,神经成像发现和潜在的病理学.
主要方法:
- 对四名表现出描述的DMS变体的痴呆症患者的回顾性分析.
- 标准化的神经心理电池用于评估认知领域.
- 使用MRI,18F-FDG-PET,DaT扫描和CSF生物标志物进行诊断的多学科共识.
主要成果:
- 这四名患者都在痴呆症的背景下出现了妄想,表现出情绪行为问题和功能衰退.
- 神经成像揭示了前端对象的时间性低代谢,主要在右半球.
- 在所有病例中,CSF生物标志物都表明阿尔茨海默氏症病理;两名患者被诊断为可能患有勒维体痴呆症.
结论:
- 描述了一种新的DMS变体",动画图片综合症",其特点是相信静态图像中的个体的活力.
- 这种综合症在神经退行性疾病中出现,与认知和功能衰退相吻合.
- 识别这种综合症有助于识别临床恶化和指导干预.
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