使用加拿大长度衰老研究来检查牙脱落和部骨矿物质密度之间的关联
Jenalyn L Yumol1,2, Diane P Dupont3, Wendy E Ward1,2
1Department of Kinesiology, Brock University, St. Catharines, ON, Canada.
Frontiers in dental medicine
|March 11, 2026
概括
在50-85岁的加拿大人中,牙数量与关节骨矿物质密度 (BMD) 没有显著的联系. 然而,较少的牙与低骨质的人的下部BMD相关,但正常骨质的人的部BMD较高.
科学领域:
- 老年学是指老年学的学科.
- 口腔健康 口腔健康
- 骨质疏松症研究 骨质疏松症研究
背景情况:
- 加拿大的骨质疏松症诊断面临着进入障碍,需要使用替代风险识别方法.
- 口腔健康指标,如牙计数,可以提供有关骨质疏松症等系统性健康状况的见解.
研究的目的:
- 调查50-85岁的加拿大成年人的牙数量和骨矿物质密度 (BMD) 之间的关联.
- 为了确定牙计数是否可以作为骨质疏松风险的预测指标.
主要方法:
- 利用了加拿大长度老龄化研究 (CLSA) 中20629名参与者的横截面数据.
- 收集了牙数量 (<或≥20颗牙),人口统计,生活方式因素以及通过双重X射线吸收计测量部 BMD 的数据.
- 采用多重线性回归和后期T分数分类进行分析.
主要成果:
- 在对共变量进行调整后,在总样本中没有发现牙数量和部骨质量之间的显著关联.
- 在子组中观察到一个显著的关联:较少的牙与低骨质 (P=0.040) 的下部BMD相关,而正常骨质 (P<0.001) 的部BMD较高.
- 在骨质疏松症组中没有发现显著的关联 (P=0.360).
结论:
- 仅仅是牙计数并不是50-85岁的加拿大普通人口中部骨硬度的可靠指标.
- 在正常和低骨质群体中的不同关联需要进一步调查.
- 未来的研究应该探索结合口腔健康指标,以提高部BMD的预测.
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