在经过迷你透性神经质透后,女性患者发生败血性休克的危险因素分析
Wen Deng1,2, Jiabiao Dai1, Jinkang Lin1
1Department of Urology, the First Affiliated Hospital of Nanchang University, Nanchang, China.
Translational andrology and urology
|March 11, 2026
概括
经过微透皮性神经脊髓损伤 (PCNL) 后的败血性休克很少见,但致命. 女性的主要危险因素包括肥胖,糖尿病,免疫抑制和手术前的尿路感染,需要主动管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
背景情况:
- 经过迷你穿皮性神经 (迷你PCNL) 后的败血性休克的发病率很低,但死亡风险很高.
- 在接受小PCNL的女性患者中确定感染性休克的危险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 在接受小PCNL的女性患者中确定感染性休克的独立风险因素.
- 提出预防和治疗小PCNL后败血症休克的管理策略.
主要方法:
- 在2021年1月至2025年3月期间接受小型PCNL的920名女性患者的回顾性分析.
- 使用后勤回归分析 (单变量和多变量) 来确定独立的风险因素.
主要成果:
- 19名患者 (2.07%) 发生了败血性休克; 2人死于多个器官功能障碍综合征.
- 确定了独立的危险因素:BMI ≥28 kg/m2 (OR=1.235),糖尿病 (OR=2.874),之前的免疫抑制剂 (OR=1.815),以及手术前的尿路感染 (OR=1.217).
结论:
- 肥胖,糖尿病,免疫抑制和手术前的尿路感染是女性迷你PCNL后感染性休克的重要危险因素.
- 建议包括预防性抗生素,严格的血糖控制,以及在手术前管理免疫系统疾病.
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