六个人类指数与结石之间的关联:基于人口的横截面研究
Xuan Zhou1, Feng Shi2, Zijian Zhou3
1Department of Urology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Translational andrology and urology
|March 11, 2026
概括
这项研究发现,身体脂肪分布增加和代谢功能障碍与美国成年人结石 (KS) 的更高患病率有关. 脂质积累产品 (LAP) 成为识别有发展KS风险的个体的关键指标.
科学领域:
- 代谢健康 代谢健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 人类测量学 人类测量学.
背景情况:
- 身体脂肪分布和代谢健康是造成结石 (KS) 形成的潜在因素.
- 人类测量指标与KS患病率之间的准确关系需要进一步阐明.
研究的目的:
- 调查六个人类指数与美国成年人结石 (KS) 患病率之间的关联.
- 使用先进的建模技术,识别KS的关键预测因素.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2007-2018) 的横截面分析.
- 对六个人类指数的评估:ABSI,LAP,TG/HDL-C,TyG,VAI和WTI.
- 应用多变量逻辑回归,受限立方线回归 (RCS) 和XGBoost模型用于关联和预测分析.
主要成果:
- 总共有14,132名成年人被分析,其中9.6%患有KS.
- 高水平的ABSI,LAP,TG/HDL-C,TyG,VAI和WTI与增加的KS患病率显著相关.
- 脂质积累产品 (LAP) 和内脏脂肪率指数 (VAI) 显示与KS患病率有非线性关系.
- XGBoost模型确定LAP是KS最强的预测因素.
结论:
- 身体脂肪分布,代谢健康标志物和美国成年人中KS患病率之间存在积极关联.
- 脂质积累产物 (LAP) 作为确定患有结石的个体的可靠预测指标.
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