Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Gut-Brain Axis01:22

Gut-Brain Axis

The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such as...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Electroacupuncture Combined With Paroxetine Improves Depression-Like Behavior in Rats by Regulating SIRT2/AMPAR in the Hippocampal Dentate Gyrus.

Journal of integrative neuroscience·2026
Same author

Single-cell analysis reveal cell-type-specific RNA methylation patterns in breast cancer.

The Journal of international medical research·2025
Same author

Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via <i>Fn1</i> in a Parkinson's Disease Model: Transcriptomic Evidence.

Journal of integrative neuroscience·2025
Same author

CUMS stress facilitates hippocampal neural mitophagy through FIS1/MFF-mediated mitochondrial fragmentation.

Journal of neurophysiology·2025
Same author

Single Herbal Medicine for Insulin Resistance: Protocol for a Systematic Review and Meta-Analysis of Randomized Clinical Trials.

JMIR research protocols·2025
Same author

Electroacupuncture ameliorated locomotor symptoms in MPTP-induced mice model of Parkinson's disease by regulating autophagy via Nrf2 signaling.

Journal of neurophysiology·2025

相关实验视频

Updated: May 12, 2026

Behavioral and Network Pharmacology-Based Analyses for the Traditional Mongolian Medicine Zadi-5 in a Rat Model of Depression
07:58

Behavioral and Network Pharmacology-Based Analyses for the Traditional Mongolian Medicine Zadi-5 in a Rat Model of Depression

Published on: February 24, 2023

951

通过电重新配置肠道植物:一种策略,以抵消老鼠的抑郁症症状.

Yuhui Tan1, Yuebei Wu1, Zhuying Chen1

  • 1School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, People's Republic of China.

Neuropsychiatric disease and treatment
|March 11, 2026
PubMed
概括

电可以通过改变肠道细菌来帮助缓解抑郁症. 这项研究发现EA调节了Akkermansia的丰富性,可能会影响大脑-肠轴.

关键词:
在阿克克曼斯的阿克克曼西亚.大脑-肠轴 - 大脑-肠轴抑郁 抑郁症 抑郁症 抑郁症 抑郁症电针是一种电针.胃肠道的微生物群

更多相关视频

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

1.1K
Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

681

相关实验视频

Last Updated: May 12, 2026

Behavioral and Network Pharmacology-Based Analyses for the Traditional Mongolian Medicine Zadi-5 in a Rat Model of Depression
07:58

Behavioral and Network Pharmacology-Based Analyses for the Traditional Mongolian Medicine Zadi-5 in a Rat Model of Depression

Published on: February 24, 2023

951
Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

1.1K
Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

681

科学领域:

  • 神经科学是一个神经科学.
  • 微生物学 微生物学
  • 综合医学是一个整体的医学.

背景情况:

  • 抑郁症是一个重要的全球健康问题.
  • 针,特别是电针 (EA),显示出作为一种治疗的希望.
  • 肠道微生物群和抑郁症之间的联系需要进一步调查.

研究的目的:

  • 为了研究电针 (EA) 和抑郁行为之间的关系.
  • 为了检查EA如何影响肠道微生物群组成,在老鼠抑郁症模型中.
  • 探索肠-大脑轴在EA抗抑郁作用中的潜在作用.

主要方法:

  • 利用16S rRNA高通量测序来分析肠道微生物群.
  • 在Sprague-Dawley大鼠中使用了慢性不可预测的轻度压力 (CUMS) 模型.
  • 在对照组,CUMS和EA治疗组进行行为分析和微生物群测序.

主要成果:

  • 电针 (EA) 治疗改变了CUMS大鼠的肠道微生物群社区结构.
  • 在EA调节了细菌Akkermansia的丰富性.
  • 这些变化表明与肠-大脑轴调节的潜在联系,包括压力和炎症通路.

结论:

  • 电针 (EA) 可能会产生抗抑郁作用.
  • 调节Akkermansia的丰富性是一个潜在的机制.
  • 这突显了脑肠轴在EA对抑郁症治疗影响中的作用.