萨科佩尼亚指数与中心肥胖症之间的关联:年龄和性别特定的模式和临床影响
Ya-Hui Lee1, Wen-Bin Bai2, Yueh Lin1
1Department of Family Medicine, Chang-Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
International journal of general medicine
|March 11, 2026
概括
较低的sarcopenia指数 (SI) 与中心肥胖症的增加有关,特别是在年轻男性和老年女性中. 这种肌肉质量生物标志物可能有助于识别患腹部肥胖风险的个体.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 老年学是一门学科.
背景情况:
- 中心肥胖是心脏代谢疾病的重要危险因素.
- 反映肌肉质量的sarcopenia指数 (SI) 与不同的人口统计数据中的肥胖现象型有着不清楚的关联.
- 了解SI在肥胖中的作用对于有针对性的健康干预至关重要.
研究的目的:
- 调查SI和中心与外围肥胖之间的关系.
- 确定SI是否是中心肥胖的一个独立预测因素.
- 建立最佳的SI截止值,以在中国大人口中识别中心肥胖症.
主要方法:
- 一项对10,054名成年人进行的回顾性横截面研究.
- 数据包括人体测量,生物化学和身体成分 (生物电阻分析).
- 使用后勤回归和ROC曲线分析来评估SI关联和中心肥胖的最佳切断值.
主要成果:
- 在24.4%的参与者中发现了中心肥胖症,与较差的心脏代谢特征相关.
- 在患有中心肥胖的人群中观察到较低的SI水平,特别是年轻男性和老年女性.
- 最低的SI三位数独立地与年轻男性 (aOR 1.27) 和老年女性 (aOR 3.03) 的中心肥胖相关;SI显示女性中度预测能力 (AUC 0.687),但男性能力有限 (AUC 0.534).
结论:
- 降低SI独立地与更高的中心肥胖率有关,特别是在年轻男性和老年女性中.
- SI可以作为一种实用的生物标志物,用于识别患有中心脂肪症风险的个体,特别是女性.
- 需要进一步的前性研究来证实SI在中心肥胖症中的预测价值.
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