探索手术结果与精神疾病之间的关系:关于术后抑郁症和焦虑症的数据库挖掘研究
Meiping Shi1, Jieying Wang1, Lulu Wang1
1Department of Anesthesiology, The Sixth Medical Center of PLA General Hospital, Beijing, China.
International journal of psychiatry in medicine
|March 11, 2026
概括
手术后的抑郁和焦虑影响了14.3%的手术患者,关节骨折手术后的风险更高. 这些情况增加了住院时间,再入院和成本,需要有针对性的干预措施.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 医疗服务研究 医疗服务研究
背景情况:
- 手术后的抑郁和焦虑是手术后的重大问题.
- 了解它们的频率,风险因素和医疗保健影响对于患者护理至关重要.
- 人口规模的数据可以为这些外科手术期间的精神病学结果提供全面的见解.
研究的目的:
- 使用人口规模的行政数据量化术后抑郁症和焦虑症的发生率.
- 为了确定与手术后这些精神疾病相关的关键风险因素.
- 评估术后精神疾病对医疗保健利用和成本的影响.
主要方法:
- 美国医疗保健成本和利用计划国家住院样本 (HCUP-NIS) 数据库 (2016-2022) 的回顾性队列分析.
- 包括47个州的420万次手术手术.
- 在手术后30天内使用ICD-10代码 (F32.x,F41.x) 识别术后精神疾病.
- 应用多变量后勤回归和倾向分数匹配来评估风险因素和医疗保健利用差异.
主要成果:
- 新诊断的术后精神疾病的总体频率为14.3% (抑郁症9.1%,焦虑症8.7%).
- 部骨折手术 (aOR 2.34),胸切除术 (aOR 1.89) 和心脏手术 (aOR 1.67) 的风险明显更高.
- 相关的风险因素包括女性性别 (aOR 1.43),年龄>65岁 (aOR 1.28) 和手术持续时间>5小时 (aOR 1.52).
- 倾向匹配分析表明,精神病患者的住院时间较长 (13.2 vs 8.4天),30天再入院率较高 (28.9% vs 19.6%),总成本增加 (47,680美元 vs 31,250美元).
结论:
- 在手术专业之间,术后精神疾病风险存在显著的异质性.
- 术后抑郁症和焦虑症大大增加了医疗保健的利用率和成本.
- 对于高风险的外科患者群体,建议进行系统的精神病学查和有针对性的术后干预.
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