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Updated: Mar 12, 2026

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
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菌类非特异性过氧酶的结构导向共同进化,以改善静脉疾病3C25-氧化通过基质结合口袋工程

Xia Ke1,2,3, Kai-Rui Wang1,2,3, Tong Zheng1,2,3

  • 1State Key Laboratory of Green Chemical Synthesis and Conversion, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.

Journal of agricultural and food chemistry
|March 11, 2026
PubMed
概括

一种新的结构导向策略快速演化了真菌非特异性过氧酶 (UPO) 以实现有效的维生素D3C25-氧化. 这种加速的酶工程实现了5.16倍的基化效率和更高的产品产量.

关键词:
这就是Pichia pastoris.石灰二醇的使用方法共同进化的共同进化酶工程是指酶工程的工程.选择性基化是一种选择性基化.不特定的过氧酶酶.

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