相关实验视频
Updated: Mar 13, 2026

08:39
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
5.5K
将患者的声音纳入属性和水平选择,进行偏好研究:对非肌肉侵入性膀癌进行定性研究
Brad Mason1, Anthony Eccleston2, Lara Ayala-Nunes3
1Adelphi Values Patient-Centered Outcomes, Bollington, UK. brad.mason@omc.com.
The patient
|March 11, 2026
概括
患有高风险非肌肉侵入性膀癌 (HR-NMIBC) 的患者优先考虑治疗有效性和安全性. 了解这些偏好对于开发新疗法和以患者为中心的护理策略至关重要.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 医疗保健服务研究 医疗服务研究
背景情况:
- 目前治疗高风险非肌肉侵入性膀癌 (HR-NMIBC) 的标准治疗包括Bacillus Calmette-Guerin (BCG) 的膀瘤转尿管切除后治疗 (TURBT).
- 新兴疗法,包括与BCG结合的免疫检查点抑制剂 (ICI),为HR-NMIBC患者提供新的治疗途径.
- 患者偏好研究对于了解当前和新兴治疗方法的权衡至关重要,为以患者为中心的护理提供信息.
研究的目的:
- 从HR-NMIBC患者中引起治疗优先事项.
- 评估患者偏好调查的属性和水平的初步列表.
- 收集有关HR-NMIBC治疗决策驱动因素的定性见解.
主要方法:
- 一个有针对性的文献审查确定了11个治疗属性的初始列表.
- 在美国,对12名HR-NMIBC患者进行了半结构化,多方法的电话采访.
- 概念诱导,认知汇报和评级/排名练习评估了患者的优先事项和对治疗属性的观点.
主要成果:
- 对所有患者来说,治疗疗效,特别是无事件生存率是最重要的属性.
- 对患者来说,严重或危及生命的事件的风险也是非常重要的考虑因素.
- 膀相关问题和给药偏好 (路线,频率) 是治疗选择的关键因素.
结论:
- 这项研究提供了关于患者对未来HR-NMIBC治疗的偏好的新型定性数据.
- 这些发现将为即将到来的利益与风险偏好研究的属性选择和框架提供指导.
- 需要进行进一步的研究,以量化患者在治疗管理,益处和风险方面的权衡.
相关概念视频
Urinary Bladder
4.0K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
4.0K
Imaging Studies I: Kidney, Ureter, and Bladder Studies
567
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
567
Imaging Studies VI: Voiding Cystourethrography and Cystography
3.0K
Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
3.0K
Assessment of the Gastrointestinal System II: Health Perception Pattern
566
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
566
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
1.1K
The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
1.1K

