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Updated: Mar 13, 2026

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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Published on: July 5, 2019

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FET融合蛋白扰乱生理学DNA修复,并为ATR抑制剂治疗创造一个有针对性的机会

Daniel E Gracilla1, Shruti Menon1, Marcus R Breese2

  • 1Memorial Sloan Kettering Cancer Center New York, NY United States.

Cancer research
|March 11, 2026
PubMed
概括

针对具有遗传突变的癌症中的DNA修复途径提供了新的希望. 这项研究揭示了FET融合基蛋白如何破坏DNA损伤反应,确定ATR是FET重组癌症的潜在治疗标.

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