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Updated: Mar 13, 2026

Detection of Aggregation-Prone Behavior in Mutant P53 V157F Breast Cancer Cells Using Multipoint Thioflavin T Fluorescence
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无活化CDKN2AARF促进p53-独立的PDAC瘤微环境的重塑

Sofia Ferreira1, Brittany M Flowers1, Won-Young Choi2

  • 1Stanford University Stanford, CA United States.

Cancer research
|March 11, 2026
PubMed
概括

由CDKN2A基因编码的瘤抑制剂ARF抑制胰腺管腺癌 (PDAC) 的发展,并独立于p53.3重新塑造瘤微环境 (TME). 这种ARF缺陷促进了PDAC的进展和治疗耐药性.

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