血友病发病率的区域变化和趋势:全球分析与未来预测
Md Mothashin1, Md Golam Hossain1,2, Sajal Chandra Barmon1
1Health Research Group, Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh.
PLOS global public health
|March 11, 2026
概括
全球血友病患病率从2014年至2023年增加,欧洲的患病率最高. 预测显示持续增长,需要在全球范围内加强监测和公平护理策略.
科学领域:
- 血液学 血液学 血液学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 血友病是一种罕见的遗传性出血障碍,需要持续监测,以告知医疗保健规划和患者的结果.
- 了解全球流行,趋势和未来预测对于资源分配和疾病管理至关重要.
研究的目的:
- 评估血友病的全球流行,时间趋势和未来预测.
- 为了确定血友病发病率的区域差异和显著的趋势变化.
主要方法:
- 世界血友病联合会 (WFH) 全球调查数据 (2014-2023) 的回顾性分析.
- 使用引导重新抽样进行流行率估计;通过线性回归和连接点分析进行趋势分析.
- 通过线性推断来预测未来的流行率.
主要成果:
- 全球血友病患病率从每10万人中2.75上升到3.75 (2014-2023),欧洲的患病率最高 (7.14-9.16).
- 欧洲,美洲和亚洲都出现了显著的上升趋势. 值得注意的国家特定峰值包括马其顿 (22.02) 和加拿大 (10.79).
- 预计到2030年,全球患病率将达到4.87,欧洲预计将达到9.66.
结论:
- 全球血友病的患病率有所增加,主要是由于诊断,意识,数据收集和治疗进展的改善.
- 到2030年预计的增长突显了加强监测,扩大诊断和公平护理的需要,特别是在高流行率地区.
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