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Updated: Mar 13, 2026

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
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在哺乳动物时钟中发现MARK2作为PER2的生理激酶

Yuxiang Liu1, Yang Li1, Tenghui Yu2

  • 1Chinese Institute for Brain Research, Beijing (CIBR), Beijing, China; Chinese Institutes for Medical Research, Beijing (CIMR), Capital Medical University, Beijing, China; Laboratory of Neurochemical Biology, Peking-Tsinghua Center for Life Sciences, Peking-Tsinghua-NIBS (PTN) Graduate Program, School of Life Sciences, Beijing, China; Department of Chemical Biology, College of Chemistry and Chemical Engineering, Beijing, China; School of Pharmaceutical Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China.

Cell chemical biology
|March 11, 2026
PubMed
概括

微管类亲和调节酶2 (MARK2) 稳定了PER2蛋白,调节了昼夜时钟. 马克2缺乏缩短昼夜周期,推进睡眠阶段,揭示了它的生理意义.

关键词:
对于FASP来说,这是一个很好的方法.马克2是什么意思在 PER2 中, PER2 是 PER2 的代码.S662 酸化的方法生物化学净化 生物化学净化昼夜时钟是生物周期的时间表.

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