过早出生儿童中期儿童患病率:一项加拿大队列研究
Sumera Aziz Ali1, Ye Shen2, Jeffrey N Bone2
1Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
The Journal of pediatrics
|March 11, 2026
概括
过早出生的儿童在5至10岁之间面临各种健康问题的更高风险. 这些风险随着更早的妊娠年龄 (GA) 的增加而增加,突出显示了对早产婴儿的持续监测和早期干预的需要.
科学领域:
- 儿科 儿科 儿科
- 新生儿科学 新生儿科学
- 公共卫生 公共卫生
背景情况:
- 早产与潜在的长期健康后果有关.
- 了解与妊娠年龄相关的儿童发病率对于有针对性的干预至关重要.
研究的目的:
- 评估早产儿中期 (5-10岁) 患各种疾病的风险.
- 识别特定的健康状况及其与不同程度的早产有关.
主要方法:
- 在不列颠哥伦比亚省 (2004-2017) 进行基于人口的队列研究.
- 对5岁至10岁的儿童进行随访.
- 孕期年龄 (GA) 分类;用于计算调整后危险比率 (AHRs) 的考克斯比例危险模型.
主要成果:
- 在510,424名儿童中,9.50%是早产儿,患病率高于按时出生的儿童.
- 观察到一种剂量反应关系:较低的GA与过敏,心脏,神经和呼吸系统疾病的风险增加相关.
- 具体的AHR表明,与按期出生的儿童相比,早产组的青春期障碍,心脏,神经和呼吸系统疾病的风险显著增加.
结论:
- 过早出生的儿童在中年童年期间有明显增加多种疾病的风险.
- 鉴定的风险随着妊娠年龄的下降而升级,这强调了持续监测和积极的健康管理对这一群体的重要性.
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