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Updated: Mar 13, 2026

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通过蛋白质O-glucosyltransferasePOGLUT2进行EGF重复O-糖化的结构基础

Yuying Xia1, Xinlin Hu2, Zhengkang Hua3

  • 1Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases and Hubei Key Laboratory of Natural Active Polysaccharides, Huazhong University of Science and Technology, Wuhan, China; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The Journal of biological chemistry
|March 11, 2026
PubMed
概括

我们阐明了人类蛋白质O-葡萄糖转移酶2 (POGLUT2) 的结构和机制,这是一个对蛋白质O-葡萄糖化至关重要的酶. 这为了解POGLUT2相关的人类疾病提供了一个框架.

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