认知功能障碍和疲劳是否会影响患有多发性硬化症的人对疾病的看法?
Raquel Portugal-Haraki1, Paloma Peter Travassos Zaidan1, Jessica Monique Dias Alencar1
1Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.
Arquivos de neuro-psiquiatria
|March 11, 2026
概括
多发性硬化症 (MS) 的疾病感知与疲劳,生活质量和残疾有关. 认知功能没有显著影响患者如何感知他们的MS疾病.
科学领域:
- 神经学 神经学
- 心理学 心理学 心理学
背景情况:
- 多发性硬化症 (MS) 是一种慢性,不可预测的神经疾病,影响身体,心理和社会福祉.
- 疾病感知,患者对疾病的看法,影响健康和治疗坚持.
研究的目的:
- 评估患有多发性硬化症 (pwMS) 的人的疾病感知.
- 确定认知功能障碍和疲劳对MS疾病感知的影响.
主要方法:
- 涉及30名RRMS患者的横截面试验调查.
- 使用了简要的疾病感知问卷 (B-IPQ),MoCA-BR,MFIS-BR和MSQOL-54.
- 收集的人口统计,临床数据和扩展残疾状况量表 (EDSS) 评分.
主要成果:
- 在认知表现和疾病感知之间没有发现显著的相关性 (p=0.761).
- 在疾病感知和疲劳领域 (p<0.001),EDSS (p=0.034) 和MSQOL-54分数 (p<0.001) 之间观察到显著的相关性.
- 40%的患者认为MS是一种重大威胁.
结论:
- 在MS中,疾病的感知受到疲劳,生活质量和残疾的显著影响.
- 认知功能似乎不是MS疾病感知的一个重要因素.
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