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Updated: Mar 13, 2026

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碳离子放射治疗的多角度光束范围测量框架使用商用多层电离室

Soorim Han¹, YongCheol Kwon¹, Taegeon Oh¹

¹Department of Radiation Oncology, Heavy Ion Therapy Research Institute, Yonsei Cancer Center, Yonsei University Health System, Seoul, the Republic of Korea.

Zeitschrift fur medizinische Physik

|March 11, 2026

概括

这项研究引入了一种高效的多层电离室 (MLIC) 框架,用于精确的碳离子放射治疗光束范围验证. 新方法显著减少了质量保证时间,改善了常规质量保证和机器一致性检查.

科学领域:

医学物理医学物理
放射治疗物理物理
辐射检测和测量辐射检测和测量

背景情况:

精确的光束范围验证在碳离子放射治疗中至关重要,因为它存在独特的物理挑战.
传统的水幻影方法对于常规质量保证 (QA) 是耗时的.

研究的目的:

开发和验证使用多层电离室 (MLIC) 进行碳离子束范围验证的高效框架.
显著减少全面质量保证测量所需的时间.

主要方法:

使用商业MLIC,采用基于光束模型的安装方法和参考积分深度剂量曲线.
实现了一个时间优化的,无触发器的采集过程,以及用于多角度测量的通道兼容的挂件.
通过范围转移实验评估测量不确定性,通过稳定性和一致性测试评估临床可行性.

主要成果:

实现了低范围的测定不确定性 (0.24 mm,k=3),与水幻影测量 (0.03 ± 0.15 mm) 非常一致.
所有能量水平的测量时间从超过50小时缩短到大约15分钟 (>100倍改进).
证明了高稳定性 (长期0.17毫米,多角度0.05毫米,k=1) 并确定了传统QA忽略的机器不一致性.

结论:

拟议的基于MLIC的框架为碳离子治疗中的常规光束范围QA提供了可靠,准确和高效的解决方案.
该框架可用于在所有能级和门架角度进行频繁,全面的验证,从而提高患者的安全性.

关键词:

测量光束范围的测量.碳离子辐射疗法碳离子辐射疗法门架照射系统的辐射系统.多层电离室多层电离室质量保证质量保证质量保证

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