当婴儿微生物引导母亲的牛奶时
Rosemary Abdoul Ahad1, Nora Joseph1, Ziad Al Nabhani1
1Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern 3010, Switzerland; Maurice Müller Laboratories, Department for Biomedical Research, University of Bern, Bern 3008, Switzerland.
Trends in microbiology
|March 11, 2026
概括
早期婴儿的肠道微生物组合影响母乳营养素和代谢物水平. 这一发现揭示了母婴二合体内的双向沟通,挑战了以前的假设.
科学领域:
- 微生物组研究 微生物组研究
- 孕产妇和婴儿的健康
- 营养科学 营养科学
背景情况:
- 传统上,母乳微生物组被视为婴儿肠道微生物殖民的主要驱动因素.
- 对于从婴儿肠道到母乳成分的潜在反机制的理解有限.
研究的目的:
- 调查早期婴儿肠道微生物群状态是否可以预测母乳营养素和代谢物的后续变化.
- 探索母婴二合体内发育定时反循环的概念.
主要方法:
- 婴儿肠道微生物组合的纵向分析.
- 随着时间的推移,测量母乳营养素和代谢物概况.
- 统计建模以确定婴儿微生物组和母乳参数之间的相关性.
主要成果:
- 早期婴儿肠道微生物组状态被发现可以显著预测母乳营养素和代谢物度的后来的变化.
- 有证据表明,来自婴儿肠道的反机制会影响母乳成分.
结论:
- 这项研究挑战了牛奶影响婴儿肠道微生物的单向模型.
- 婴儿肠道微生物组和母乳之间存在双向通信系统,突出显示出一个动态的母婴二合体.
- 这些发现对理解婴儿发育,母亲健康和营养规划有影响.
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