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在子囊与膜内皮质甲状腺小癌之间进行热除结果的回顾性多中心研究

Haoyu Jing¹, Qiyang Chen¹, Mingbo Zhang²

¹Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

|March 11, 2026

概括

对于亚囊性乳头甲状腺微癌 (PTMC) 的热移除 (TA) 产生了与内PTMC相似的结果. 这种微侵袭性治疗表现出类似的疾病进展和生存率,支持其用于亚囊结节的使用.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
最少侵入性的手术

背景情况:

乳头甲状腺微瘤 (PTMC) 是一种常见的甲状腺恶性瘤.
亚囊PTMC位置对治疗提出了独特的挑战.
热除 (TA) 是PTMC的一个新兴的微创性选择.

研究的目的:

评估和比较亚囊PTMC与内PTMC的TA临床结果.
根据与甲状腺囊相对的PTMC位置来评估TA的疗效和安全性.

主要方法:

对497名单焦,节点阴性PTMC接受TA的患者进行了回顾性研究 (2015年7月至2021年12月).
患者分为子囊 (囊距离≤2mm) 和囊内 (>2mm) 组.
倾向性得分匹配 (PSM) 用于平衡混因素;主要结果:疾病进展,无疾病生存期 (DFS).

主要成果:

在PSM后的组之间,疾病进展 (4.3%对3.8%) 或5年DFS (93.2%对93.9%) 没有显著差异.
可比的二次结局包括并发症率 (1.6%对1.1%) 和瘤消失率 (98.9%对99.5%).
多变量分析显示,亚囊位置与疾病进展之间没有关联 (HR=1.3,p=0.59).

结论:

对于亚囊PTMC和内PTMC,TA实现了可比的4年临床结果.
TA是一种安全有效的治疗选择,用于囊下和内PTMC.
需要进一步的前性研究来证实这些发现.

关键词:

热性消去是热性消去的一种.微波除是微波除的一种方法.甲状腺小瘤是甲状腺小瘤.无线电频率剥离方式超声波超声波是指超声波的使用.

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