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怀孕前BMI与中国妇女早产之间的关联:一项回顾性研究

Qing Li¹, Xinyi Lu², Jun Zhang³

¹Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University, Shanghai, China.

Annals of medicine

|March 12, 2026

概括

怀孕前体重不足与中国妇女早产风险无关,但超重和肥胖显著增加了PTB风险. 观察到PTB风险最低的BMI在18.5-21.5 kg/m2之间,风险值约为24.5 kg/m2.

科学领域:

产科和妇科产科和妇科
生殖健康生殖健康
流行病学流行病学

背景情况:

怀孕前的体重指数 (BMI) 是影响怀孕结果的关键因素.
了解怀孕前BMI (PPBMI) 和早产 (PTB) 之间的关联对于公共卫生倡议至关重要,特别是在多样化的人口中.
以前的研究表明,BMI类别和PTB之间存在不同的关联,因此需要对特定人群进行调查.

研究的目的:

在一个大型的中国队列中,研究妊娠前BMI (PPBMI) 和早产风险 (PTB) 之间的关系.
在这个人群中确定与增加或减少PTB风险相关的特定PPBMI范围.
使用先进的统计方法,探索PPBMI和PTB之间的潜在非线性关联.

主要方法:

一项回顾性队列研究,涉及中国72,827例单胎怀孕.
参与者被分为四个PPBMI组:体重不足 (<18.5公斤/米2),正常体重 (18.5-23.9公斤/米2),超重 (24-27.9公斤/米2) 和肥胖 (≥28公斤/米2).
使用后勤回归和受限制的立方线来分析PPBMI和PTB之间的关联,并对混因素进行调整.

主要成果:

整体PTB的发病率为4.8%.
与正常体重相比,体重不足类别 (轻度,中度,严重) 与PTB风险没有显著关联.
超重 (aOR=1.32) 和肥胖 (aOR=1.47) 与增加PTB风险显著相关.
PPBMI和PTB风险之间的关联遵循J形曲线,在PPBMI之间观察到的最低风险为18.5-21.5 kg/m2,潜在风险值约为24.5 kg/m2.

结论:

怀孕前体重不足与中国人口中早产风险增加没有显著关联.
在怀孕前超重和肥胖是中国妇女早产的重要危险因素.
这些发现表明J形关系,突出最佳的PPBMI范围以尽量减少PTB风险,并确定干预的关键值.

关键词:

华人中文华人中文是什么意思在怀孕前的BMI 过早出生过早出生这是一个值.体重不足是因为体重不足.

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