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Updated: Mar 13, 2026

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay
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关于NTSR1 G蛋白亚型乱交的动态基础的快照

Alina A Vo1, Arnab Modak2, Sumin Lu3

  • 1Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA.

Nature
|March 12, 2026
PubMed
概括

了解G蛋白亚型选择性至关重要. 这项研究揭示了短暂的中间状态,而不仅仅是无核酸复合体,决定了像NTSR1.1这样的受体对G蛋白的选择.

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