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Updated: Jun 12, 2026

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胺基的功能核酸的新设计

Zhiming Zhang1, Meng Jiang1, Axin He1

  • 1Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou, China.

Nature computational science
|March 12, 2026
PubMed
概括

使用核酸大语言模型 (NA-LLM) 的新框架 InstructNA 能够高效地设计功能性核酸 (FNA). 它产生多样化,高亲和度的体和DNA结合剂,优于传统方法.

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