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Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
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声波刺-Gli1信号通过IKKβ/NF-κB通路促进微质激活

Zhi-Rou Xu1, Kan Wu1, Rui-Ying Guo1

  • 1The Affiliated Guangji Hospital of Soochow University, Jiangsu Key Laboratory of Drug Discovery and Translational Research for Brain Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.

Acta pharmacologica Sinica
|March 12, 2026
PubMed
概括

微质中的Sonic Hedgehog (Shh) -Gli1通路在帕金森病模型中促进神经炎症和多巴胺基神经元损伤. 抑制这种途径可以减少炎症并保护神经元.

关键词:
通过NF-κB路径.帕金森病的疾病.索尼克刺信号发送的信号微质细胞中的微质细胞神经炎症是一种神经炎症.

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