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Updated: Mar 13, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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一个工程外细胞囊,增强了瘤和淋巴结的向,作为siRNA输送系统,用于强大的瘤免疫疗法

Yusi Wang1, Rui Zhang1, Xuejing Zhou1

  • 1Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital Sichuan University Chengdu China.

MedComm
|March 12, 2026
PubMed
概括

携带瘤抗原和向的工程外细胞囊泡 (EVs) 显示出增强的积累和改善的免疫反应. 这种新型的癌症疫苗平台DP-EVs/siPD-L1通过激活抗瘤免疫力和逆转免疫抑制,有效抑制瘤生长.

关键词:
细胞外囊泡中的细胞外囊泡.免疫反应激活免疫反应激活siRNA的传递方式瘤免疫疗法 免疫疗法瘤微环境重编程

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