内脏脂肪质量指数与糖尿病和血管并发症的关联:NHANES 2011-2018横截面研究
Yao Wang1,2, Xingyu He1, Guangya Xu3
1Clinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu, Sichuan 610081, China.
Health data science
|March 12, 2026
概括
高内脏脂肪质量指数 (vFMI) 显著增加患糖尿病及其血管并发症的风险,包括糖尿病病和心血管疾病.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 由内脏脂肪质量指数 (vFMI) 表示的内脏肥胖是胰岛素抵抗和心血管功能障碍的已知危险因素.
- 了解vFMI与糖尿病及其血管并发症之间的联系对于公共卫生至关重要.
研究的目的:
- 调查内脏脂肪质量指数 (vFMI) 与糖尿病患病率之间的关联.
- 检查糖尿病患者vFMI和血管并发症之间的关系,特别是糖尿病病 (DN) 和心血管疾病 (CVD).
主要方法:
- 利用了2011-2018年全国健康和营养检查调查 (NHANES) 的数据.
- 包括成年参与者 (18岁以上) 在分析中.
- 使用多变量逻辑回归和非线性回归来评估关联并确定风险值.
主要成果:
- 较高的vFMI四分位数与糖尿病,DN和CVD的几率增加密切相关.
- 确定了危险的vFMI值 (0.252对于糖尿病,0.241对于DN),风险升级.
- 在年轻人 (≤40岁) 中观察到更强的关联,那些 triglycerides 较低的人,和更好的β细胞功能.
结论:
- 较高的内脏脂肪质量指数与较高的糖尿病患病率及其相关的血管并发症有显著的相关性.
- 内脏脂肪的积累在糖尿病和相关血管问题的发病过程中起着关键作用.
- 向减少内脏脂肪可能是管理糖尿病和预防其并发症的关键策略.
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