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Updated: Mar 13, 2026

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维索米丁作为一种通过SYK抑制在AML中的差异化诱导治疗剂

Byeol-Eun Jeon1, Chan-Seong Kwon1, Ji-Eun Lee1

  • 1Department of Integrated Biological Science, College of Natural Sciences, Pusan National University, Busan, Republic of Korea.

Frontiers in pharmacology
|March 12, 2026
PubMed
概括

维索米丁是一种针对线粒体的抗氧化剂,通过促进癌细胞分化和亡,有效治疗急性髓性白血病 (AML). 它选择性地向AML细胞,通过ROS抑制SYK,显示作为一种新型AML治疗的希望.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.灭症 (apoptosis) 是一种死亡的过程.不同化的差异化差异化.药物重新定位 药物重新定位有活性氧物种的反应性氧物种.与脏相关的氨酸激酶

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