长期阻塞性尿路病变的双重收集系统中的尿道状细胞癌:一个罕见的病例报告
Mahesh Bahadur Adhikari1, Ajit Khadga1, Ravi Kiran Gautam1
1Department of Urology and Renal Transplant, Nepal Mediciti, Lalitpur, Nepal.
International journal of surgery case reports
|March 12, 2026
概括
尿道状细胞癌 (SCC) 是一种罕见的癌症,通常是晚诊断的. 这一案例突显了双重系统中炎症驱动的致癌症,强调了早期诊断和彻底的手术以获得更好的结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 尿道的状细胞癌 (SCC) 是一种罕见的,激进的恶性瘤 (1-1.6%的上道尿癌).
- 慢性刺激的石头,水,或感染可以触发状形质变形和恶性转变.
- 尿道SCC的晚期诊断有助于预后不佳.
研究的目的:
- 在双重收集系统中呈现尿道SCC病例.
- 要突出与慢性石头疾病和由炎症驱动的致癌症的关联.
- 强调早期诊断和多学科管理的重要性.
主要方法:
- 一名57岁的男性出现了虚弱,减肥和失尿症的症状,接受了评估.
- 与对比度增强的CT显示了双重左与水溶解,尿道结石和远端尿道质量.
- 进行了带有部分囊切除的腹腔镜激进瘤切除术 (RNU),随后进行了他的病理学分析.
主要成果:
- 组织病理学证实中度差异化SCC (G2) 侵入尿周脂肪和淋巴血管入侵.
- 邻近的状元形成和发育不良支持炎症-癌症序列.
- 手术边缘是负的 (R0),脏显示慢性肺炎.
结论:
- 双重系统中的尿道SCC可能来自慢性炎症和石头疾病.
- 通过切除膀袖口进行彻底脏切除术是主要的治疗方法.
- 由于瘤的侵袭性质,对成像和囊镜进行密切的随访至关重要.
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