结核患者糖尿病查:系统性审查和元分析
Unjali P Gujral1, Peijue Huangfu2, Amanuel A Kisho3
1Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
糖尿病 (DM) 在结核病 (TB) 患者中很常见. 结核病患者的DM查结果为7.8%的患病率,东地中海和东南亚地区的患病率更高. 早期检测可以改善结果.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 结核病 (TB) 是一个重要的全球卫生问题,在2023年有1080万新病例.
- 糖尿病 (DM) 增加了结核病的风险和恶化了结核病的结果,结核病流行地区的DM患病率上升.
- 在结核病患者中,早期发现和管理DM可能会改善健康结果.
研究的目的:
- 系统地审查和对结核病患者中DM查的收益进行元分析.
- 确定在被诊断为结核病的人群中DM的患病率.
主要方法:
- 2000年1月至2025年9月期间发表的研究的系统审查和元分析.
- 包括33项研究,涉及19581名微生物确诊结核病患者.
- 采用随机效应元分析汇集数据,按世卫组织地区和年龄分层.
主要成果:
- 在结核病患者中,DM查的整体综合收益率为7.8% (95% CI:5.1-11.1).
- 收益率因地区而异,从太平洋西部的2.6%到地中海东部的31.6%.
- 在东地中海和东南亚地区观察到更高的DM流行率.
结论:
- 在结核病患者中,DM经常被检测到.
- 特定地区的DM查收益率更高,与DM患病率相关.
- 需要进一步的研究来优化结核病患者的DM检测策略.
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