外体膜氧化治疗严重流感相关的肺:一个病例报告
Cuijie Tian1, Chaofan Liang2, Xinyan Zhang2
1Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Frontiers in medicine
|March 12, 2026
概括
流感相关的肺炎 (IAPA) 是一种严重的真菌共感染. 这一案例强调了静脉静脉外体膜氧化 (VV-ECMO) 和支气管镜作为气道侵入性IAPA的救援策略.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 流感相关的肺阿斯伯吉洛症 (IAPA) 是一种危及生命的疾病.
- 它越来越多地影响非经典免疫受损的个体.
- 这份报告详细介绍了一起严重的病例,有严重的气道侵袭.
研究的目的:
- 描述严重IAPA的临床过程和管理.
- 评估VV-ECMO和支气管镜在耐火病例中的作用.
主要方法:
- 一个34岁的女性患有流感A (H1N1) 的病例报告,并怀疑IAPA.
- 使用了侵入性机械通风,VV-ECMO,诊断支气管镜,BALF显微镜和mNGS.
- 治疗包括全身和局部抗真菌疗法 (安福特 B) 和呼吸道清除.
主要成果:
- 确认了Aspergillus fumigatus与A型流感 (H1N1) 的同时感染.
- 患者经历了难治性急性呼吸衰竭与极端的气道阻力.
- 从VV-ECMO成功断奶,并在处理后放出.
结论:
- 静脉静脉外体膜氧化 (VV-ECMO) 可能是一个救援策略.
- 重复的支气管镜干预对于气道侵入性IAPA至关重要.
- 这种综合方法在一些耐火性呼吸衰竭患者中有效.
相关概念视频
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
817
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
817
Pneumonia III: Complications and Assessment
1.4K
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.4K
Pneumonia IV: Management
1.2K
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
1.2K
Acute Respiratory Failure-II
1.8K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.8K
Acute Respiratory Failure-V
768
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
768
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
749
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
749


