在挪威奥斯陆地区实施糖尿病视网膜病变查:为期3年的试点研究
Ellen Steffenssen Sauesund1,2, Cathrine Brunborg3, Øystein Kalsnes Jørstad1,2
1Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.
Frontiers in medicine
|March 12, 2026
概括
在奥斯陆的糖尿病视网膜病变 (DR) 查发现,在基线时,糖尿病视网膜病变的患病率为27.8%. 糖尿病持续时间和白蛋白尿是DR在三年内进展的关键风险因素.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病视网膜病变 (DR) 是糖尿病患者视力丧失的主要原因.
- 通过查计划及早发现和管理对于预防严重视力障碍至关重要.
- 试点查计划有助于评估DR检测策略的有效性和可行性.
研究的目的:
- 为了确定糖尿病视网膜病变 (DR) 在三年中的患病率和进展情况.
- 在试点查计划中确定与DR进展相关的风险因素.
- 在奥斯陆地区评估DR查计划的实用性.
主要方法:
- 在试点查计划中招募了90名患有1型或2型糖尿病的成年患者.
- 使用 fundus 摄影和光学连贯性断层扫描 (OCT) 进行年度 DR 查.
- 分析了社会人口统计数据,糖尿病病史,HbA1c,血压和尿液中白蛋白与肌素的比率;用于风险因素分析使用考克斯回归.
主要成果:
- 基线DR患病率为27.8%,其中6.7%具有视力威胁DR (VTDR).
- 在三年内,24.7%的患者经历了DR进展,4%患有VTDR.
- 糖尿病持续时间 (HR 1.07) 和尿中的白蛋白与肌素比率 (HR 1.03) 是DR进展的显著预测因素.
结论:
- 大多数患者在为期三年的研究期间保持了稳定的DR.
- 糖尿病持续时间和白蛋白尿是DR进展的显著预测因素.
- 基于风险的分层可能允许延长低风险糖尿病患者的查间隔.
更多相关视频
10:38DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens
Published on: February 1, 2020
8.0K
11:06Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care
Published on: November 11, 2022
3.4K
相关概念视频
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Nephrotic Syndrome III : Nursing Management
549
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
549
Diabetic Retinopathy
55
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
55
Diabetic Nephropathy
32
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration...
32
