孕妇补充功能性纤维可以通过在怀孕期间调节肠道微生物群来改善生殖性能
Shengnan Yin1, Jinghua Cheng1, Mu Wang1,2
1College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
Frontiers in microbiology
|March 12, 2026
概括
补充功能性纤维的孕期饮食改善了母猪的表现,增加了出生和健康的小猪总数. 这种饮食干预也增强了肠道微生物群的稳定性和弹性,像NK4A214_group这样的特定细菌与小猪健康有积极的相关性.
科学领域:
- 动物科学动物科学
- 微生物组研究 微生物组研究
- 营养生理学 营养生理学
背景情况:
- 孕期饮食显著影响母猪的表现和后代的生存能力.
- 肠道微生物组的组成在孕产妇和胎儿的健康中起着至关重要的作用.
- 功能纤维作为料添加剂提供了潜在的好处.
研究的目的:
- 研究孕期饮食中的功能纤维补充对母猪表现的影响.
- 分析功能纤维对肠道微生物组合和妊娠期间稳定性的影响.
- 探索特定肠道细菌,代谢物和生殖结果之间的关系.
主要方法:
- 1000头母猪被分为对照组 (CON) 和食纤维 (DF) 组,补充1%的功能纤维 (耐性粉和瓜尔).
- 记录了母猪的表现 (出生总数,健康的小猪, litter 出生的体重,子宫内生长迟缓).
- 用测序和共发生网络分析分析了肠道微生物群的组成,多样性和网络稳定性.
- 便非向代谢学已确定了关键代谢物,包括胆汁酸.
主要成果:
- 与CON相比,DF组的出生总量,健康的小猪和 litter出生体重增加,同时减少子宫内生长迟缓 (IUGR).
- 功能性纤维补充增强了整个妊娠期间的肠道微生物多样性,稳定性和弹性.
- 特定的细菌群,NK4A214_组 (DF组) 和Treponema (CON组),显示出显著的变化和与小猪数量的相关性.
- DF组表现出胆汁酸水平的增加,如甘氨酸 (GCDCA),与NK4A214_组丰度和孕相关.
结论:
- 在孕期饮食中补充功能性纤维对母猪生殖性能和小猪健康产生积极影响.
- 肠道微生物组,特别是NK4A214_组的丰富性,在调解这些益处方面发挥着至关重要的作用.
- 甘氨酸 (GCDCA) 可能是通过与肠道细菌的相互作用来改善生殖结果的关键代谢物.
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