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饮食引起的心脏功能障碍和比格尔犬的认知能力受损

Elise Bokshowan¹, Adam M S Luchkanych¹, Matheus de O Costa^2,3

¹Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon, SK, Canada.

American journal of physiology. Regulatory, integrative and comparative physiology

|March 12, 2026

概括

狗的无谷物饮食可能会影响心脏健康和认知功能. 研究表明,饮食引起的心脏问题与大脑血流减少以及狗伴侣的认知能力下降之间存在联系.

科学领域:

兽医心脏病学兽医心脏病学
狗的营养狗的营养
神经学神经学

背景情况:

狗的饮食诱导扩张性心肌病 (DCM) 与含有豆类的无谷物饮食有关,可能是由于寡糖.
人类研究将心力衰竭与大脑血流减少和认知能力下降联系起来.

研究的目的:

调查狗的饮食诱导心脏功能障碍是否与大脑血流减少和认知能力下降相吻合.
探索不同饮食养的狗中心脏功能,大脑血流和认知功能之间的关联.

主要方法:

在一个随机的交叉设计中,八只成年比格尔被养四种饮食 (商业牙科,以谷物为基础的,以谷物为基础的拉芬,以豆为基础的无谷物) 每个5周.
用超声波评估心脏功能和大脑血流.
用沙子迷宫测试来评估认知功能.

主要成果:

与基于谷物 (GB) 和GBO的饮食相比,无谷物 (GF) 和养殖饮食的狗表现出较低的喷射分数和较大的左心室末缩体积.
基底脑动脉显示出更高的终端透析速度和导电率指数,以及在GF和养殖饮食中的狗中较低的电阻指数.
通过沙子迷宫检索时间测量认知功能,与GBO饮食相比,在养GF和养殖饮食的狗中,认知功能更慢.

结论:

减少狗的射出分数与较低的脑血管度和认知功能受损有关,特别是在那些食GF和养殖饮食的狗中.
这项研究表明,狗的饮食,心脏功能和认知之间存在潜在的联系,突出了对无谷物和含豆的饮食进行进一步研究的需要.

关键词:

大脑血液流动的大脑血液流动认知认知认知扩张性心肌病症扩张性心肌病症狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗一种类型的寡糖.

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