高密度电解剖绘图和MRI的比较:在非缺血性心肌病的肌肉心脏表征方面迈出了一步
Michela Casella1, Leonardo D'Angelo2, Maria L Narducci3
1Cardiology and Arrhythmology Clinic, Marche University Hospital, Ancona, Italy; Department of Clinical Specialistic and Odontostomatologic Sciences, Marche Polytechnic University, Ancona, Italy; Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.
JACC. Clinical electrophysiology
|March 12, 2026
概括
电解剖学电压映射 (EVM) 显示与非血性心肌病 (NICM) 患者的晚期加多增强心磁共振 (LGE-CMR) 痕图高度一致. 这支持EVM.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 电子生理学 电子生理学
背景情况:
- 在非缺血性心肌病 (NICM) 中,突然心脏死亡 (SCD) 风险分层取决于确定心肌痕.
- 晚期加多增强心磁共振 (LGE-CMR) 是痕评估的标准.
- 来自LGE-CMR的3D痕图可以与电解剖学电压映射 (EVM) 集成.
研究的目的:
- 评估LGE-CMR衍生的痕地图与EVM之间的一致性和可靠性.
- 用高密度导管EVM评估心肌组织的表征.
主要方法:
- 一项多中心的观察性研究包括36名接受EVM的NICM患者.
- 进行LGE-CMR并进行处理,以划分痕核心和边界区域.
- EVM使用了全极技术 (OT),双极 (BIP) 和单极 (UNI) 模式;科恩的kappa和Bland-Altman方法评估了一致性和可靠性.
主要成果:
- UNI的配置与心下LGE-CMR图表 (κ: 0.93) 有着很强的一致性.
- 全极技术 (OT) 对心下内脏层的双极技术 (BIP) 的表现优于双极技术 (κ: 0.97 vs 0.74).
- OT表现出与LGE-CMR痕地图一致的最少偏差和最窄的界限.
结论:
- EVM与LGE-CMR具有很高的一致性,准确地划分了内心中心肌底.
- 在NICM患者中,EVM显示了基质表征的潜力.
- 这种技术对于不适合LGE-CMR的患者是有价值的.
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