Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Body Temperature01:25

Body Temperature

5.2K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
5.2K
Body Temperature01:07

Body Temperature

1.7K
Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
1.7K
Hypodermis01:02

Hypodermis

8.3K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
8.3K
Thermoregulation01:26

Thermoregulation

2.9K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
2.9K
Metabolic Rate01:25

Metabolic Rate

1.3K
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
1.3K
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

7.2K
7.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The effect of timing of physical exercise on glycemia: a systematic review and meta-analysis of human intervention studies.

Journal of diabetes and metabolic disorders·2026
Same author

Predictive equations fail to accurately assess resting metabolic rate in international elite male volleyball players.

American journal of physiology. Endocrinology and metabolism·2025
Same author

Glycerolipid Cycling in Thermogenesis, Energy Homeostasis, Signaling, and Diseases.

Physiological reviews·2025
Same author

GDF15 links adipose tissue lipolysis with anxiety.

Nature metabolism·2025
Same author

The effect of altered sleep timing on glycaemic outcomes: Systematic review of human intervention studies.

Diabetes, obesity & metabolism·2024
Same author

The effects of the β<sub>1</sub>-adrenergic receptor antagonist bisoprolol administration on mirabegron-stimulated human brown adipose tissue thermogenesis.

Acta physiologica (Oxford, England)·2024

相关实验视频

Updated: Mar 13, 2026

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

2.1K

棕色脂肪组织的热生成.

Denis P Blondin1,2

  • 1Department of Medicine, Division of neurology, Université de Sherbrooke, Sherbrooke, QC, Canada.

Physiology (Bethesda, Md.)
|March 12, 2026
PubMed
概括

人类棕色脂肪组织 (BAT) 是一个动态的器官,影响新陈代谢和温度调节. 研究探讨了其生物分子特征,激活策略,以及在代谢健康中的作用,尽管仍存在不确定性.

科学领域:

  • 内分泌学和新陈代谢学
  • 脂肪组织生物学 脂肪组织生物学
  • 热生成研究 热生成研究

背景情况:

  • 人类棕色脂肪组织 (BAT) 以其在温度调节和基质新陈代谢中的作用而闻名.
  • 了解BAT的功能对于解决心脏代谢健康至关重要.
  • 最近的研究强调了BAT的动态性质和潜在的治疗影响.

研究的目的:

  • 审查人类棕色脂肪组织 (BAT) 的当前知识.
  • 综合有关BAT生物分子特性,激活方法和功能意义的信息.
  • 确定BAT研究中不确定性的关键领域.

主要方法:

  • 文献综述综合人类的BAT数据.
  • 对BAT脂肪细胞的分子分析研究的分析.
  • 检查用于测量BAT in vivo功能的成像技术.
  • 对BAT激活的生理和药理刺激的审查.

主要成果:

  • 人类BAT的特点是异质脂肪细胞具有多局部脂质滴,丰富的内化,血管化和线粒体.
  • 暴露在寒冷中是一种强大的BAT激活剂,营养和药物刺激也表现出影响.
  • 图像技术的进步允许量化BAT热生成,这表明BAT在能源消耗中的作用很小,但与心脏代谢风险降低有关.
关键词:
棕色脂肪组织的脂肪组织.脂肪组织脂肪组织.热生成是一种热生成.热源性脂肪细胞 (thermogenic adipocytes) 是一种热源性脂肪细胞.温度调节 温度调节

更多相关视频

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
04:46

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

2.5K
Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
10:30

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

9.5K

相关实验视频

Last Updated: Mar 13, 2026

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

2.1K
Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
04:46

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

2.5K
Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
10:30

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

9.5K

结论:

  • 人类的BAT在温度调节和基质利用中发挥作用,有助于代谢健康.
  • 尽管取得了进展,但在BAT的热生成能力和激活途径方面仍然存在重大不确定性.
  • 需要进一步进行综合的多模式研究,以充分阐明BAT对代谢健康的贡献.