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Updated: Mar 13, 2026

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
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A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

Published on: December 22, 2020

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PI3K和MAPK信号节点作为癌症相关纤维细胞的表型可塑性在结肠直肠癌中的不同驱动因素

Zihan Xia1, Felix De Vuyst1, Sam Ernst1

  • 1Ghent University Ghent Belgium.

Cancer research
|March 12, 2026
PubMed
概括

与癌症相关的纤维细胞 (CAFs) 显示出影响瘤生长的多种亚型. 针对PI3K/mTOR和MAPK/ERK通路可以重新编程这些CAF,为结直肠癌 (CRC) 提供新的治疗策略.

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Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies09:01

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