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Updated: Mar 14, 2026

Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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切换c-Myc蛋白降解路径取决于PP2A-B55α复合物的水平

Sana Ando1, Shunta Ikeda1, Keiko Tanaka1

  • 1Laboratory of Veterinary Pharmacology, Joint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi 753-8515, Japan.

Proceedings of the National Academy of Sciences of the United States of America
|March 12, 2026
PubMed
概括

蛋白酸酶2A (PP2A) -B55α通过两个不同的途径控制c-Myc基蛋白降解. 这一发现解决了PP2A的悖论.

关键词:
这就是PPP2R2A.这就是PPP2R2D.这就是UBR5 UBR5.c-Myccc 的意思是我的蛋白酸酶2A是一种蛋白酸酶.

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