通过在成药物诊所的多式综合护理计划,改善直接作用抗病毒药物的获取
Arya Zandvakili1, Joseph Rattenni2,3, James Burton4
1Division of Infectious Diseases, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
The American journal on addictions
|March 12, 2026
概括
将C型肝炎病毒 (HCV) 护理整合到成医学诊所中,增加了直接作用抗病毒 (DAA) 的启动. 这种实用模型提高了注射药物使用史的患者获得HCV治疗的机会.
科学领域:
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
- 成 药物 药物 药物 药物
背景情况:
- 注射药物使用是导致C型肝炎病毒 (HCV) 传播的主要驱动因素.
- 将HCV护理整合到成治疗中对于HCV消除策略至关重要.
研究的目的:
- 描述HCV护理在成医学 (AM) 诊所的整合.
- 评估这种综合护理模式对HCV治疗结果的影响,特别是直接作用抗病毒药物 (DAA) 的启动,完成和持续的病毒学反应 (SVR).
主要方法:
- 综合护理包括在AM诊所内进行HCV查和DAA治疗处方,或通过远程医疗与传染病专家 (ID) 进行远程医疗.
- 进行了回顾性图表审查,以评估计划实施前后的DAA启动,完成和SVR率.
- 统计分析,包括危险比率 (HR) 和p值,用于比较结果.
主要成果:
- 整合后,DAA启动率显著增加 (HR 2.21),每月发行更多的DAA处方.
- 综合护理导致肝病学转诊的减少.
- 与肝病学转诊相比,直接在AM诊所处方DAA与DAA启动率 (HR 42.46) 和完成率 (HR 8.33) 相对较高.
结论:
- 综合性HCV护理,包括面对面和远程医疗的选择,改善了获得DAA治疗的机会.
- 该模型展示了成医学和传染病专家之间的跨专业合作,以加强HCV护理的价值.
相关概念视频
01:30Specialized Care Centers and Settings-II
1.3K
Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
1.3K
01:28Drug Therapy
364
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
364
01:29Therapeutic Drug Monitoring: Affecting Factors
313
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
313
01:22Drug Delivery: Miscellaneous Routes
928
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
928
01:28Acute Coronary Syndrome IV: Interprofessional Care
376
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
376
01:17Drug Dependence
1.8K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.8K