习惯性饮食改变会通过影响卵巢发育和Bombyx mori (Lepidoptera: Bombycidae) 的营养积累来降低卵子的质量和数量
Guang Wang1,2, Lu Ma1,2, Chen Yang1,2
1School of Life Sciences, Suzhou Medical College, Soochow University, Suzhou, China.
Journal of economic entomology
|March 12, 2026
概括
人工饮食通过破坏20-hydroxyecdysone (20E) 信号来损害丝虫的繁殖,影响卵子的发育和后代的生存能力. 补充20E恢复了生殖能力,为丝培养干预提供了洞察力.
科学领域:
- 昆虫学 昆虫学是一门学科.
- 动物繁殖 动物繁殖
- 生物化学 生物化学
背景情况:
- 工业化丝农业越来越多地为丝虫 (Bombyx mori) 使用人工食 (AD).
- 在ADS上养丝虫会导致生殖能力受损,这是一个具有不清楚潜在机制的重大挑战.
研究的目的:
- 阐明人工饮食对丝虫生殖能力产生负面影响的机制.
- 调查20-基乙 (20E) 信号在饮食引起的生殖能力下降中的作用.
主要方法:
- 丝虫在整个幼虫阶段都被人工养.
- 在幼阶段分析了荷尔蒙水平 (20E) 和蛋白质合成 (vitellogenin, 30Kc19).
- 给出了外源的20E补充剂,以评估其对生殖能力的影响.
主要成果:
- 人工饮食在幼发育过程中抑制了20-基乙 (20E) 信号传递.
- 这种抑制干扰了维特洛根因和30Kc19的合成和运输,导致卵巢异常和糖原缺乏.
- 用外源的20E补充剂成功恢复了女性的生殖能力.
结论:
- 这项研究发现,受损的20E信号传递是食人工食的虫生殖能力下降的关键机制.
- 这种干扰会影响卵子发育,卵子质量和后代的生存能力,带来跨代后果.
- 这些发现为开发干预策略提供了理论基础,以改善丝虫在丝养殖中的繁殖性能.
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