由Oropouche病毒的核细胞向非结构蛋白调解RNA聚合酶II降解和干扰素对抗作用

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Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution

Published on: January 16, 2017

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Rokusuke Yoshikawa1,2, Yoshiyasu Ishii2,3, Naomi Sano2

  • 1Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.

The Journal of infectious diseases
|March 12, 2026
PubMed
概括

奥罗普什病毒非结构性蛋白 (NSs) 通过向RNA聚合酶II来抑制宿主转录,以便在核中降解. 这种免疫逃避机制部分抑制了I型干扰素的信号传输,提供了潜在的抗病毒点.

关键词:
国际货币基金组织-I耳鼻病毒病毒的RNA聚合酶II.具有天生的免疫力.核细胞定位信号的信号

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