患者报告的长期胃肠道结果在患有腹和胃的儿童:A PedsQL GI模块研究研究
Maaike Hogerwerf1,2,3,4, Adinda G H Pijpers1,3,4, Ramon R Gorter1,3,4
1Department of Pediatric Surgery, Amsterdam Pediatric Abdominal Center, Emma Children's Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.
概括
患有腹的儿童很少经历长期的胃肠道问题. 然而,那些患有胃症的人报告气体增加,胀气,腹和便秘,需要有针对性的治疗.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床结果研究研究
背景情况:
- 长期胃肠道 (GI) 结局在患有腹和胃症的患者是可变的.
- 之前的研究缺乏标准化的方法,阻碍了直接比较.
- 需要进行系统的评估,以了解患者报告的胃肠道症状.
研究的目的:
- 系统地评估患者报告的长期胃肠道症状,用于治疗腹和胃肠裂的儿童.
- 将胃肠道症状得分与健康的对照队列进行比较.
- 为了确定这些患者群体中受影响的特定的胃肠道领域.
主要方法:
- 在1999年至2022年期间接受了腹或胃治疗的儿童被邀请完成儿科生活质量清单GI模块.
- 根据年龄,使用了父母的代理报告或儿童的自我报告.
- 评分与预定义的美国健康队列 (n=513) 进行了比较,使用Bonferroni校正的显著性 (p<0.004).
主要成果:
- 总共有45名患者 (20名腹骨,25名胃) 填写了调查问卷.
- 奥姆法洛塞尔患者报告的胃肠道症状得分与健康对照组相似 (p>0.01).
- 与对照组相比,胃分裂患者报告气体和胀气 (p=0.001),腹 (p=0.002) 和便秘 (p=0.026) 的得分明显较差.
结论:
- 脊髓灰质炎患者长期经历的胃肠道症状负担较低,这表明例行随访可能不必.
- 胃症患者表现出更高的患有特定的胃肠道问题 (气体,胀气,腹,便秘).
- 早期识别和针对性地管理胃肠道症状对于胃肠分裂幸存者至关重要.
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