孕期帕沃病毒B19感染:从系统性审查和元分析中得出的围产期结果
Sara Sorrenti1, Eileen Deuster2, Francesco D'Antonio3
1Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Italy; Fetal Medicine Unit, Liverpool Women's Hospital, Liverpool.
American journal of obstetrics and gynecology
|March 12, 2026
概括
在怀孕期间的帕沃病毒B19感染会导致严重的胎儿和围产期并发症. 虽然像子宫内死亡这样的结果在最近和过去的爆发之间没有区别,但胎儿MRI在需要子宫内输血的情况下显示出高比例的异常脑部发现.
科学领域:
- 周围生理学 周围生理学
- 传染性疾病 传染性疾病
- 胎儿医学 胎儿医学
背景情况:
- 怀孕期间的帕尔沃病毒B19感染对胎儿和围产期的结果构成风险.
- 了解不同疾病波的结果对于临床管理至关重要.
研究的目的:
- 为了评估孕期帕尔沃病毒B19感染的胎儿和围产期结局.
- 为了比较最近 (2023-2024) 和以前的疾病浪潮之间的结果.
主要方法:
- 一项对44项涉及3221名妇女和748名胎儿的研究进行的元分析.
- 搜索了MEDLINE,EMBASE,SCOPUS,科学网,科克伦图书馆和CINAHL (2000年至2025年4月). 搜索结果包括:
- 使用随机效应模型进行聚合比例和元回归进行波浪比较.
主要成果:
- 胎内死亡率为胎儿感染的38.7%,母亲感染的7.3%.
- 胎儿贫血的超声波迹象包括水 (58.7%) 和心血管大病 (39.0%).
- 最近和之前的波之间的子宫内死亡或贫血症状没有显著差异;最近的波中子宫内输血的数量更高 (p=0.09).
结论:
- 怀孕期间的帕尔沃病毒B19感染与高围产期发病率和死亡率有关.
- 最近的爆发结果与以前的关于子宫内死亡的浪潮相似.
- 在IUT病例中产前MRI显示出高水平的异常脑部发现,这表明它在诊断中的潜在作用.
关键词:
在2023-2024年爆发疫情.负面的怀孕结果.胎儿贫血症 胎儿贫血症在Hydrops fetalis中使用.在子宫内输血输血.孕产妇感染的感染帕尔沃病毒B19 B19周产期的 周产期的怀孕的结果 怀孕的结果第五种疾病第五种疾病死亡率 死亡率打了一下脸综合症.更多相关视频
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