职业接触来自水泥添加剂的反:特异化和健康风险见解
Maria Chiara Fontanella1, Elena Serena2, Davide Guarascio2
1Department for Sustainable Food Process, DiSTAS, Università Cattolica del Sacro Cuore, Via E. Parmense 84, Piacenza, 29122, Italy.
Chemosphere
|March 12, 2026
概括
反 (Sb) 越来越令人担忧,尤其是其致癌三价形式. 这项研究开发了一种方法来追踪水泥中的Sb物种,发现三价抗氧化物在材料和空气中占主导地位,低于暴露限值.
科学领域:
- 环境科学 环境科学
- 分析化学 分析化学
- 职业健康 职业健康 职业健康
背景情况:
- (Sb) 是一种新兴的环境污染物,存在持久性,生物积累和毒性问题.
- 三价抗[Sb(III) ]是一种可疑的人类致癌物.
- 在水泥中使用基于Sb的添加剂来减少有毒的六价[Cr(VI) ],但Sb的环境命运和职业暴露尚不清楚.
研究的目的:
- 开发和验证一种分析方法,用于在水泥工业矩阵中区分[Sb (III) /Sb (V) ]的反物种.
- 评估在水泥处理过程中对的环境命运和职业暴露.
- 描述工业材料和空气中的颗粒物中的反物种化.
主要方法:
- 开发了一个强大的分析工作流程,使用酸-EDTA提取与HPLC-ICP-MS/MS相结合.
- 验证了氧化状态保存和回收率高达68%的方法.
- 将工作流应用于商业添加剂,预混合水泥和工人的个人空气过器.
主要成果:
- Sb (III) 被确定为散装水泥材料和空气中的颗粒物中占主导地位的反物种.
- 空气中的Sb度在0.00004至0.00114毫克m-3之间,低于国际职业暴露限值.
- 该方法证明了有效的氧化状态保存.
结论:
- 在材料和空气中的颗粒中Sb(III) 的占主导地位凸显了化学特异对于准确的职业暴露评估的重要性.
- 经过验证的工作流提供了一个实用的工具,用于在水泥生产中监测反物种.
- 这项研究支持基于证据的抗暴露在水泥行业的风险管理策略.
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