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Updated: Mar 14, 2026

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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

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PHB2通过NEDD4L依赖的NCOA4 ubiquitination改善铁和大动脉动脉瘤/解剖

Shengjun Xiong1, Jie Lin1, Ying An1

  • 1Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, China; State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, China; National Health Commission (NHC) Key Laboratory of Ischemic Heart Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, Shanghai, China; Key Laboratory of Viral Heart Diseases, National Health Commission, Shanghai, China.

Redox biology
|March 12, 2026
PubMed
概括

禁素2 (PHB2) 抑制细胞死亡途径铁亡,在血管光滑肌细胞中,防止大动脉动脉瘤和解剖 (AAD). 针对PHB2-NEDD4L-NCOA4轴为AAD提供了一个潜在的治疗策略.

关键词:
动脉剖析是一个大动脉剖析.铁化是铁化的一种.没有NCOA4的在NEDD4L中,它是NEDD4L.在 PHB2 中,我们可以使用 PHB2.在Ubiquitination中使用.

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