动态胃肠道模拟显示,短期果粉调节食 (多) 代谢,肠道微生物群和代谢活动
Salud Cáceres-Jiménez1, Natalia Molinero2, Carolina Cueva2
1Departamento de Bromatología y Tecnología de los Alimentos, Campus Rabanales, Ed. Darwin-anexo Universidad de Córdoba, 14071 Córdoba, Spain.
Food research international (Ottawa, Ont.)
|March 12, 2026
概括
果中的多可通过增加有益细菌和在消化和发酵过程中产生黄油酸等有益化合物来显著提高肠道健康. 这项研究强调了果.
科学领域:
- * 营养科学 营养科学
- * 微生物学 微生物学
- * 胃肠病学 胃肠病学
背景情况:
- *饮食中的多醇被肠道微生物群广泛代谢.
- *果富含 (多) ,但其体内命运和对肠道微生物群的影响尚未完全理解.
- *了解这些相互作用对于利用果的健康益处至关重要.
研究的目的:
- * 评估果 (多) 对肠道微生物群组成和代谢活性的影响.
- * 调查在胃肠道消化和结肠发酵过程中果 (多) 的转化.
- * 评估果消费对短链脂肪酸 (SCFA) 生产和水平的影响.
主要方法:
- *动态胃肠道模拟器 (simgi®) 模拟消化和发酵.
- * 果泥以健康捐赠者的便微生物群为食.
- *UHPLC-HRMS用于 (多) 分析,用于微生物分析的16SrRNA测序,以及SCFA/氨的确定.
主要成果:
- * 果 (多) 在结肠中被广泛代谢,产生诸如和肉酸等有益化合物.
- * 在结肠发酵过程中,聚醇总含量显著增加.
- * 果养增加了有益细菌 (例如,Bifidobacterium spp. ),黄油酸生产,以及降低含量.
结论:
- *果 (多) 经历显著的微生物转化,产生生物活性代谢物.
- * 果的消费积极调节肠道微生物群的组成,增强新陈代谢活动.
- *果通过多代谢和有益的微生物转移促进更健康的肠道环境.
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