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鼻腔隔膜偏差与估计的肺动脉压力范围审查之间的关联

Samuel A Collazo¹, Kimberly A Ramirez², Nareg H Roubinian³

¹Department of Otolaryngology - Head and Neck Surgery, Kaiser Permanente Oakland Medical Center, Oakland, California, USA.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

|March 12, 2026

概括

鼻隔膜偏差手术显著降低了肺动脉压力. 这份对9项研究的综述发现,肺动脉平均估计压力 (mPAP) 和静脉压力 (ePASP) 在分管整形术后下降,这表明鼻腔阻塞和心脏功能之间存在联系.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
心脏病学心脏病学
肺部病理学肺部病理学

背景情况:

鼻隔膜偏差 (NSD) 是慢性上呼吸道阻塞 (UAO) 的常见原因.
包括NSD在内的UAO可能会影响心肺功能,特别是肺动脉压力.
鼻腔分管术是NSD的常见手术,用于改善气流.

研究的目的:

进行现有文献的范围审查.
确定和检查NSD,估计的肺动脉平均压力 (mPAP) 和估计的肺动脉缩压力 (ePASP) 之间的关系的证据.
为了评估鼻腔分管术后这些压力的变化.

主要方法:

根据PRISMA扩展范围审查指南进行的范围审查.
搜索了包括PubMed,EMBASE和Ovid在内的数据库.
包括9项前后研究,共458名参与者 (395名血清整形,63名对照).

主要成果:

所有包括的研究都报告了经过鼻腔整形术后手术后mPAP和/或ePASP的统计学上显著下降 (p <0.05).
两项研究显示,NSD患者和对照人群之间的手术前mPAP显著不同 (p < 0.001).
在NSD的手术纠正后,肺动脉压力显著降低.

结论:

本综述突出显示了NSD与肺动脉压力 (mPAP,ePASP) 之间存在联系的证据.
鼻腔整形似乎可以降低与NSD相关的肺动脉压力升高.
需要进一步进行高质量的研究来确定因果关系并探索UAO与心肺的联系.

关键词:

平均肺动脉压力肺动脉压力鼻腔隔膜偏差鼻腔隔膜偏差鼻腔隔膜整形术是指鼻腔隔膜整形术.肺动脉缩压力肺动脉缩压力

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