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Updated: Jul 6, 2026

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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代谢依赖和神经前体调节障碍:儿童高度质瘤发展的驱动力

Yan Hay Grace Lee1,2, Maria Tsoli1,2, Yan Chuan Shi3,4

  • 1Children's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, Sydney, NSW, Australia, Sydney, NSW, Australia.

Cancer metastasis reviews
|March 13, 2026
PubMed
概括

儿科高度质瘤 (pHGGs) 是一种侵袭性的儿童大脑瘤. 了解它们的分子亚型,表观遗传变化和代谢脆弱性是开发针对性治疗这些致命疾病的关键.

关键词:
神经前代细胞是神经前代细胞.儿科高等级质瘤瘤微环境中的微环境

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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